That’s a really long time, and it’s only an average.

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While the maximum dose of tadalafil for the treatment of erectile dysfunction may give you intense erections, it’s important to choose the right dosage for your individual needs to experience minimal side effects and avoid permanent or serious injury. In this guide, we’ll break down how tadalafil works, the available dosages, and how to take it for the best results, whether you’re aiming for spontaneity or long-term consistency. Since tadalafil is the longest-lasting medication for erectile dysfunction, it should be treated differently than many other medications on the market. The key reason: A single dose of tadalafil may provide relief from ED for up to 36 hours. If we wade into the science for a moment, that means the half-life of tadalafil is approximately 17.5 hours. In elderly men, for instance, tadalafil has a slightly longer half-life of roughly 21.6 hours.

Product Dosage Quantity + Bonus Price
Cialis Original20mg8 Pills61.70€ 58.76€
Cialis Generic5mg270 + 10 Pills205.81€ 196.01€
Cialis Professional40mg270 + 6 Pills898.37€ 855.59€
Cialis Generic5mg10 Pills29.39€ 27.99€
Cialis Generic40mg20 Pills59.47€ 56.64€
Cialis Generic5mg90 + 6 Pills115.91€ 110.39€
Cialis Generic60mg270 + 10 Pills443.96€ 422.82€
Cialis Soft Tabs20mg30 + 4 Pills87.43€ 83.27€
Cialis Soft Tabs20mg120 + 6 Pills248.64€ 236.80€
Cialis Generic60mg30 + 2 Pills85.33€ 81.27€
Cialis Professional20mg270 + 6 Pills623.07€ 593.40€
Cialis Generic40mg360 + 10 Pills477.87€ 455.11€
Cialis Professional20mg60 + 2 Pills183.83€ 175.08€
Cialis Generic2.5mg270 + 10 Pills199.64€ 190.13€

As a long-lasting ED medication, tadalafil is only recommended for use once per day.

What happens if the prescriber decides treatment is not suitable?

If you are taking tadalafil for PAH or BPH, take the missed dose as soon as you remember it. Do not take a double dose to make up for a missed one. pain in the stomach, back, muscles, arms, or legs sudden decrease or loss of vision (see below for more information) changes in color vision (seeing a blue tinge on objects or having difficulty telling the difference between blue and green) sudden decrease or loss of hearing (see below for more information) erection that lasts longer than 4 hours swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs Some patients experienced a sudden loss of some or all of their cialis soft tabs 20mg vision after they took tadalafil or other medications that are similar to tadalafil. The vision loss was permanent in some cases. It is not known if the vision loss was caused by the medication.

Financial and insurance assistance

If you experience a sudden loss of vision while you are taking tadalafil, call your doctor immediately or get emergency medical treatment. Do not take any more doses of tadalafil or similar medications such as sildenafil (Revatio, Viagra) or vardenafil (Levitra) until you talk to your doctor. Some patients experienced a sudden decrease or loss of hearing after they took tadalafil or other medications that are similar to tadalafil. The hearing loss usually involved only one ear and did not always improve when the medication was stopped. It is not known if the hearing loss was caused by the medication.

How long do you take Cialis?

If you experience a sudden loss of hearing, sometimes with ringing in the ears or dizziness, while you are taking tadalafil, call your doctor immediately. Call your doctor if you have any unusual problems while taking this medication If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online ( or by phone (1-800-332-1088). Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of unneeded medications in a way so that pets, children, and other people cannot take them. For optimal results, it’s recommended to take tadalafil at least 30 minutes before you and your partner plan to have sex.

Society and culture

Also tell your doctor if you or any of your family members have or have ever had an eye disease such as retinitis pigmentosa (an inherited eye condition that causes loss of vision) or if you have ever had sudden severe vision loss, especially if you were told that the vision loss was caused by a blockage of blood flow to the nerves that help you see. if you are a woman and you are taking tadalafil to treat PAH, tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking tadalafil, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking tadalafil. talk to your doctor about the safe use of alcoholic beverages during your treatment with tadalafil.

Before taking tadalafil,

If you drink a large amount of alcohol (more than five glasses of wine or five shots of whiskey) while you are taking tadalafil you are more likely to experience certain side effects of tadalafil such as dizziness, headache, fast heartbeat, and low blood pressure. if you are taking tadalafil to treat erectile dysfunction, tell your doctor if you have ever been advised by a health care professional to avoid sexual activity for cialis much cost medical reasons or if you have ever experienced chest pain during sexual activity. Sexual activity may be a strain on your heart, especially if you have heart disease. If you experience chest pain, dizziness, or nausea during sexual activity, call your doctor immediately or get emergency medical treatment, and avoid sexual activity until your doctor tells you otherwise. tell all your health care providers that you are taking tadalafil.

Mild side effects

If you ever need emergency medical treatment for a heart problem, the health care providers who treat you will need to know when you last took tadalafil. Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine. If you are taking tadalafil for erectile dysfunction on a regular schedule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose or more than one dose per day to make up for a missed one. But if you have sex every four hours, you won’t want to use tadalafil every time, as this could be very dangerous.

Consult with a trusted healthcare professional for personalized medical advice.

Comparing the Mechanism of Action

Ask your pharmacist for a list of the ingredients. tell your doctor if you are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Isordil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat, others). Nitrates come as tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are not sure whether any of your medications contain nitrates. Your doctor will probably tell you not to take tadalafil if you are taking nitrates.

Drug details

tell your doctor if you are taking street drugs containing nitrates ('poppers') such as amyl nitrate, butyl nitrate, or nitrite while taking tadalafil. Your doctor will probably tell you not to take tadalafil if you are taking street drugs containing nitrates. you should know that tadalafil is available under the brand names Adcirca and Cialis. You should only be treated with one of these products at a time. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take.

Sildenafil (Viagra®), Vardenafil (Levitra®), Tadalafil (Cialis™)

Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor what herbal products you are taking, especially St. John's wort. tell your doctor if you smoke; if you have ever had an erection that lasted more than 4 hours; and if you have recently had diarrhea, vomiting, not been drinking enough fluids, or sweating a lot which may have caused dehydration (loss of a large amount of body fluids. Also tell your doctor if you have or have ever had pulmonary veno-occlusive disease (PVOD; blockage of veins in the lungs); any condition that affects the shape of the penis; diabetes; high cholesterol; high or low blood pressure; irregular heartbeat; a heart attack or heart failure; angina (chest pain); a stroke; ulcers in the stomach; a bleeding disorder; blood circulation problems; blood cell problems such as sickle cell anemia (a disease of the red blood cells), multiple myeloma (cancer of the plasma cells), or leukemia (cancer of the white blood cells); or heart, kidney, or liver disease. Contrary to popular belief, tadalafil and other PDE5 inhibitors won’t make you get random erections.

Cialis Daily (Tadalafil)

Do not flush this medication down the toilet. Talk to your pharmacist about take-back programs in your community. Visit the FDA's Safe Disposal of Medicines website for more information. Keep all medication out of sight and reach of children as many containers are not child-resistant. Place the medication in a safe location – one that is up and away and out of their sight and reach.

Dosing Considerations

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. Keep a written list of all of the prescription and nonprescription (over-the-counter) medicines, vitamins, minerals, and dietary supplements you are taking.

Authors and Affiliations

Bring this list with you each time you visit a doctor or if you are admitted to the hospital. You should carry the list with you in case of emergencies. Entadfi® (as a combination product containing Finasteride, Tadalafil) Be ready for sex whenever you're in the mood Tadalafil (the active ingredient in brand names Adcirca® and Cialis®) is popular for its long duration and flexibility in dosing (which can be taken daily or as-needed), setting it apart from other erectile dysfunction (ED) meds. It lasts cialis drug cost for up to 36 hours. Its multiple dosing options can offer benefits, but they can also make knowing how to take the medication a bit confusing. Instead, proper use of tadalafil just increases blood flow to your penis, meaning

you’ll only get an erection when you receive sexual stimulation or feel sexually aroused.

Condition Recommended Range Effects if Not Followed
Temperature 20°C-25°C (68°F-77°F) Degraded potency if too hot/ cold
Humidity Low Tablet may degrade or stick
Light Exposure Avoid direct sunlight Can reduce efficacy
Packaging Keep in original container Protect from moisture

Tadalafil works by inhibiting the effects of cGMP-specific phosphodiesterase type 5 (or PDE5), an enzyme found in the smooth muscle cells of blood vessels. PDE5 plays a major role in regulating the flow of blood to certain parts of your body, including the erectile tissues of your penis.

Myth Fact Explanation
“25mg is the starting dose” Starting dose usually 10 mg 25 mg often for occasional use or specific cases
“Cialis causes immediate erection” Requires sexual stimulation Drug enhances response, does not cause erection outright
“Daily use leads to addiction” No addiction reported Safe daily use under medical supervision
“Alcohol completely negates Cialis” Moderate alcohol is usually safe Excessive alcohol reduces effectiveness