Key Considerations Before Taking Chewable Sildenafil

You should always follow your doctor’s instructions regarding sildenafil dosing, but your total daily dosage should never exceed 100 milligrams.

• Do not share your medication with others, as it may be unsafe.
• Contact a doctor if you experience prolonged erections or severe pain.
• Sildenafil should not be used with certain eye medications, consult your doctor.

Even if you’re not getting results from a sildenafil citrate 120 mg 100-milligram dose of sildenafil, don’t try to take more.

Sildenafil Citrate Chewable Tablets USP 50mg Technical Specification:

Your provider may adjust your dosage depending on your needs and how you respond to the medication. It’s also possible you may get a prescription in doses that are multiples of 20 milligrams, including 20 milligrams, 40 milligrams, 60 milligrams, and 80 milligrams. In these cases, your sildenafil tablets would actually be the generic form of Revatio®, a medication that has the ingredient sildenafil, like Viagra, but is FDA-approved for pulmonary arterial hypertension (although it can be prescribed off-label for ED). Be sure to talk through all options with your healthcare provider. And, as is the case with taking any medication, following a professional’s medical advice is crucial.

THERAPEUTIC INDICATIONS:

Unlike some other ED meds, you don’t take sildenafil every day. Sildenafil is an as-needed medication that should be taken at least about 30 minutes to an hour before sexual activity, and its effects should last up to four hours. You should never take more than one dose per day. You may be prescribed sildenafil or Viagra if you struggle with the following symptoms: Getting erections that aren't as firm as you'd like them to be Getting erections that aren't as firm as you'd like them to be Some medications can upset your stomach if you don’t take them with food. You can take this ED medication with or without food.

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However, high-fat meals can impact the absorption of sildenafil, leading to lower peak plasma levels of the medication, which can translate to lower efficacy. Grapefruit juice can also interfere with how the body processes sildenafil, leading to more side effects. So, if you’re a half-grapefruit in the a.m. kind of guy, mention that to your healthcare provider before filling a sildenafil prescription. Keep sildenafil out of the reach of children and pets, and store the medication at room temperature between 68°F to 77°F (20°C to 25°C). If sildenafil isn’t helping with your lackluster erections, there are a few possible reasons.

Another kind of treatment altogether (like therapy for psychological ED) Another kind of treatment altogether (like therapy for psychological ED) Addressing underlying health conditions that can contribute to ED Addressing underlying health conditions that can contribute to ED Additionally, taking sildenafil too early (we’re talking more than a few hours before having sex) won’t produce the effects you’re looking for. That means you have to do a bit of sex planning when taking sildenafil. But you might be surprised at how sexy the anticipation can be—for you and your partner. Spend that time exploring new foreplay ideas or sharing your sexual fantasies.

Avoid taking sildenafil if it’s expired.

According to the FDA, you should skip taking any expired meds and safely dispose of them for the following reasons: Their chemical composition could be altered, making them unsafe to consume. Their chemical composition could be altered, making them unsafe to consume. How can you tell if your medications are expired? Check the label for a date, likely next to the abbreviation “Exp.” Want more tips on how to get the most out of sildenafil?

About the Company

A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510. If your healthcare provider just prescribed sildenafil citrate (generic Viagra®) to treat your erectile dysfunction (ED) symptoms, you’re probably excited to get your mojo back. But it’s also understandable if your head is swimming with questions. Like other PDE5 inhibitors, or phosphodiesterase type 5 inhibitors, sildenafil is a safe treatment for ED, if used as directed.

Potential side effects of tadalafil

It’s been Food and Drug Administration (FDA)-approved for this use since 1998, after all. In an effort to provide some answers to your lingering questions, this guide will explain how to take sildenafil for the best results, a typical starting dosage, and potential side effects to consider. But remember that you should always follow your provider’s instructions for taking sildenafil—or any sildenafil 12 5 mg medication, for that matter. Sildenafil belongs to a class of drugs known as PDE5 inhibitors. These medications block the PDE5 enzyme, resulting in the widening of your blood vessels to promote blood flow to the penis.

Stop taking medication for ED if you notice any concerning symptoms

This increased blood flow results in an erection. However, sildenafil doesn’t affect your libido. You still need to be aroused to get and maintain an erection long enough to yield satisfying sex. Healthcare providers can prescribe sildenafil tablets in different doses. A typical starting dose of sildenafil is 50 milligrams, which you’d take 30 minutes to four hours before sexual activity. Read our guide on how to use Viagra for best results.

At a glance

Phosphodiesterase (PDE) has many isoforms and is an enzyme that has many functions in the body including degrading the effect of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). PDE5 is an enzyme that is found in many parts of the body including in the smooth muscle of the corpus cavernosum, prostate, bladder, the vascular and visceral smooth muscle, skeletal muscle, urethra, platelets, kidney, lung, cerebellum, heart, liver, testis, seminal vesicle, and pancreas. Sildenafil is structurally similar to cGMP and prevents degradation of cGMP by competitively binding and inhibiting activity of PDE5. When PDE5 is inhibited, cGMP accumulates and leads to smooth muscle relaxation. In the corpus cavernosum, this leads to penile erection.

Before taking medication for ED

In the pulmonary system, it leads to vasodilation in the pulmonary arteries. Oxytocin may possess antidiuretic effects—extended administration may increase risk of fluid overload Cardiovascular disease, due to oxytocin’s potential vasopressor effects Known hypersensitivity to sildenafil or tablet excipients Use of nitrates and alpha-blockers due to risk of life-threatening hypotension Severe hepatic impairment (Child-Pugh Class C) Severe renal impairment (creatinine clearance <30 mL/min) History of NAION (non-arteritic anterior ischemic optic neuropathy) Store at controlled room temperature (20°C to 25°C / 68°F to 77°F) Osilla EV, Patel P, Sharma S. Oxytocin. This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness.

QUALITATIVE AND QUANTITATIVE COMPOSITION:

This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of sildenafil 45 mg chewable tablets any disease or condition. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. It doesn’t really matter if you forget to take sildenafil because it’s designed for you to take it as you need it. But be careful about accidentally doubling up on doses. Missing a dose before sex is no big deal, though doing so may impact the quality of your erection. However, forgetting you already took sildenafil and taking a subsequent dose within 24 hours can lead to complications, particularly if you go over 100 milligrams total.

You should be aware of the potential side effects when taking any new drug.

Sildenafil Citrate Chewable Tablets IP 100mg Technical Specification:

Oxytocin. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: Kou J, Lan C, Zhang Y, Wang Q, Zhou F, Zhao Z, Montag C, Yao S, Becker B, Kendrick KM. Contrasting motivational effects of oral and intranasal oxytocin on arousal and reward during social processing. Oral Administration of Oxytocin, Like Intranasal Administration, Decreases Top-Down Social Attention.

STORAGE & DOSAGE:

Oxytocin causes G-protein coupled receptors to increase intracellular calcium which leads to uterine contraction. The stimulation of uterine contractions causes more oxytocin to be released. As more oxytocin is released it positively influences even more release of oxytocin. This release of oxytocin is called positive feedback which is much different than how many hormones work in the endocrine system. Oxytocin administered exogenously causes the same response as endogenously produced oxytocin.

CAUTION & SCHEDULE:

Not only does oxytocin stimulate uterine contractions, but it also causes contractions of myoepithelial cells in the alveolar ducts found in female breast tissue. These contractions force milk from these ducts into even larger sinuses, which subsequently enables milk expulsion. When a baby attempts to latch onto the mother’s breast it causes oxytocin secretion into the blood in the same manner as vaginal delivery; instead of uterine contractions, milk is ejected from the breast. Similar to the actions of oxytocin in the uterus to stimulate contractions during delivery, milk-ejection from breast tissue occurs due to positive feedback. In the brain, it is proposed that oxytocin stimulates social and sexual function by its activity in many areas of the brain including its activity on neurotransmitters. The most common side effects of sildenafil include: Most of these mild side effects will go away on their own as your body adapts to taking sildenafil. But sildenafil also comes with some more rare but potentially serious side effects like: Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Sudden loss of vision (potentially a sign of non-arteritic anterior ischemic optic neuropathy or NAION) Priapism (a painful erection lasting longer than four hours) Priapism (a painful erection lasting longer than four hours) If you experience any of these symptoms after taking sildenafil, seek immediate medical attention.

• Sildenafil works by inhibiting the enzyme PDE5, helping to relax blood vessels.
• Do not take these tablets with nitrates or certain medications without consulting a doctor.
• These tablets are suitable for people who have difficulty swallowing pills.

And FYI: Even mild side effects can impact your life. If you get an upset stomach every time you take sildenafil, talk with a healthcare professional. They may recommend changing your dose or switching medications altogether. Read more about potential sildenafil reactions in our sildenafil side effects guide.