Viagra User Reviews & Ratings

On the basis of these evaluations, the men were classified as having organic, psychogenic, or mixed erectile dysfunction.

• Viagra was originally researched to treat cardiovascular diseases.
• The medication may cause temporary loss of blue-tinted vision.
• Sildenafil is used in both brand-name Viagra and generics.
• The drug’s impact on blood vessels was a significant scientific breakthrough.
• Side effects often subside within a few hours of intake.
• Viagra’s popularity spurred further research in sexual medicine.
• Men should watch for symptoms like chest pain or sudden vision changes.
• Consulting a healthcare provider ensures personalized and safe treatment.

Of the 861 men studied, 605 (70 percent) were judged to have organic erectile dysfunction, 99 (11 percent) to have psychogenic erectile dysfunction, and 157 (18 percent) to have mixed erectile dysfunction.

• Viagra can improve quality of life for men with ED.
• It has a rapid metabolism, often cleared within 4 hours.
• Erectile dysfunction may indicate underlying health problems needing attention.
• Some people experience back pain or muscle aches as side effects.
• It is recommended to avoid fatty foods close to the time of taking Viagra.
• Using Viagra without medical supervision is unsafe.
• Erectile response to Viagra depends on psychological and physical factors.
• The medication is available at pharmacies with a valid prescription.

Men were excluded if they had penile anatomical defects, a primary diagnosis of another sexual disorder (e.g., premature ejaculation), spinal cord injury, any major psychiatric disorder not well controlled with treatment, poorly controlled diabetes mellitus,

Viagra Dosage and Administration

However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. We evaluated the efficacy and safety of sildenafil, administered as needed in two sequential double-blind studies of men with erectile dysfunction of organic, psychogenic, or mixed causes.

Sildenafil may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

In a 24-week dose–response study, 532 men were treated with oral sildenafil (25, 50, or 100 mg) or placebo. In a 12-week, flexible dose-escalation study, 329 different men were treated with sildenafil or placebo, with dose escalation to 100 mg based on efficacy and tolerance. After viagra red this dose-escalation study, 225 of the 329 men entered a 32-week, open-label extension study. We assessed efficacy according to the International Index of Erectile Function, a patient log, and a global-efficacy question. In the dose–response study, increasing doses of sildenafil were associated with improved erectile function (P values for increases in scores for questions about achieving and maintaining erections were <0.001).

What can I do to make Viagra work faster?

For the men receiving 100 mg of sildenafil, the mean score for the question about achieving erections was 100 percent higher after treatment than at base line (4.0 vs. 2.0 of a possible score of 5). In the last four weeks of treatment in the dose-escalation study, 69 percent of all attempts at sexual intercourse were successful for the men receiving sildenafil, as compared with 22 percent for those receiving placebo (P<0.001). The mean numbers of successful attempts per month were 5.9 for the men receiving sildenafil and 1.5 for those receiving placebo (P<0.001). Headache, flushing, and dyspepsia were the most common adverse effects in the dose-escalation study, occurring in 6 percent to 18 percent of the men. active peptic ulcer disease, a history of alcohol or substance abuse, major hematologic, renal, or hepatic abnormalities, or a recent (within the previous six months) stroke or myocardial infarction or if they were receiving nitrate therapy.

Other erectile-dysfunction therapies were discontinued at the time of screening (four weeks before the subjects received the study medication).

Who Should Not Take These?

To find out how the cost of sildenafil compares to the cost of Viagra, talk with your doctor or pharmacist. Optum Perks is owned by RVO Health. By clicking on this link, we may receive a commission. Viagra isn’t approved for use in females. And it hasn’t been studied in pregnant people.

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It’s unknown whether this drug is safe to take during pregnancy. In animal studies, Viagra didn’t cause fetal harm when given to pregnant animals. But animal studies don’t always predict what will happen in humans. If you have questions about the safety of Viagra use during pregnancy, talk with your doctor. It’s not known if Viagra is safe to take during pregnancy.

How to Take Sildenafil

(But keep in mind that the drug isn’t approved for use in females.) If you’re sexually active and you or your partner can become pregnant, talk with your doctor about whether you’ll need to use birth control while you’re taking Viagra. And it hasn’t been studied in people who are breastfeeding. Viagra may pass into breast best viagra for men milk, but it’s not known if this could affect a breastfed child. If you have questions about the safety of using Viagra while breastfeeding, talk with your doctor. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Sildenafil (Viagra) and an identical-looking placebo were supplied by Pfizer.

FDA Safety Communication: Revatio (sildenafil)

Sildenafil is a selective inhibitor of cyclic-GMP–specific phosphodiesterase type 5, the predominant isozyme metabolizing cyclic GMP in the corpus cavernosum.10 By selectively inhibiting cyclic-GMP catabolism in cavernosal smooth-muscle cells,11 sildenafil would be expected to restore the natural erectile response to sexual stimulation but not cause erections in the absence of such stimulation. Sildenafil is rapidly absorbed, with maximal plasma concentrations occurring within one hour after oral administration and a mean terminal half-life of three to five hours.10 In a placebo-controlled pilot study of 12 men, sildenafil significantly improved the erectile response during visual sexual stimulation.10,12 We therefore undertook two studies to evaluate in a home setting the efficacy and safety of sildenafil in men with erectile dysfunction. In two sequential studies, we studied a total of 861 men 18 years of age or older with a clinical diagnosis of erectile dysfunction (as defined previously1) of six months' duration or longer at 37 centers in the United States. Each man had to be in a stable relationship with a female partner that had begun at least six months earlier. The cause of erectile dysfunction was determined from the medical history, physical examination, and other diagnostic procedures, including a test involving the intracavernosal injection of a vasoactive drug (done in 31 percent of the men), a RigiScan test of nocturnal penile tumescence (26 percent), penile duplex ultrasonography (21 percent), and endocrine testing (21 percent). The men were instructed to take a dose approximately one hour before planned sexual activity but not more than once daily.

Before Using

Ninety-two percent of the men completed the 32-week extension study. Oral sildenafil is an effective, well-tolerated treatment for men with erectile dysfunction. Erectile dysfunction, the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance, is estimated to affect up to 30 million men in the United States.1 The disorder is age-associated,1–3 with estimated prevalence rates of 39 percent among men 40 years old and 67 percent among those 70 years old.2 The available treatments include vacuum-constriction devices; intracavernosal injections of vasoactive agents, including alprostadil (prostaglandin E1)4; transurethral delivery of alprostadil5; implantation of penile prostheses; and venous or arterial surgery. No effective oral therapy for erectile dysfunction is currently available.6 Normal penile erection depends on the relaxation of smooth muscles in the corpora cavernosa. In response to sexual stimuli, cavernous nerves and endothelial cells release nitric oxide, which stimulates the formation of cyclic guanosine monophosphate (GMP) by guanylate cyclase.7–9 The mechanism by which cyclic GMP stimulates relaxation of the smooth muscles remains to be elucidated. The protocols were approved by the institutional review board at each center, and all the men gave written informed consent.

We assessed efficacy by using the responses to question 3 (frequency of penetration) and question 4 (maintenance of erections after penetration) of the

• Viagra’s impact has driven social and medical discussions about ED.
• It is advisable to disclose all medications to your healthcare provider.
• Some individuals may require alternative treatments if Viagra is ineffective.
• The drug’s popularity has led to numerous online counterfeit products.
• Using genuine Viagra from licensed pharmacies ensures safety.
• Pregnant women and men with certain health issues should avoid Viagra.
• Common side effects tend to diminish as the body adjusts.
• Regular check-ups are recommended for men on long-term ED medication use.

15-question International Index of Erectile Function, a validated, multidimensional, self-administered questionnaire used for the clinical assessment of erectile dysfunction and treatment outcomes in clinical studies.11 The responses to these two questions pertaining to the ability to achieve and maintain an erection sufficient for sexual intercourse, as

• Viagra is considered a first-line treatment for erectile dysfunction.
• Its discovery was a breakthrough in sexual medicine.
• The drug’s molecular design targets specific enzymes to enhance blood flow.
• Viagra can sometimes cause dizziness or temporary vision loss.
• It was initially studied as a potential treatment for angina.
• Men taking Viagra often report improved confidence and intimacy.
• Sildenafil, the active compound, is now used in other medications.
• Higher doses do not necessarily mean better results and can increase side effects.

described in the definition of erectile dysfunction,1 were rated on a scale of 1 (almost never or never) to 5 (almost always or always).

A score of 0 indicated no attempt at sexual intercourse.

What Precautions Should I Take?

If you think you’ve taken too much of this drug, call your doctor. You can also call America’s Poison Centers at 800-222-1222 or use its online tool. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. Before taking Viagra, discuss your health history with your doctor. Viagra may not be right for you if you have certain medical conditions or other factors affecting your health.

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Be sure to talk with your doctor if any of the following apply to you: previous allergic reaction to Viagra, sildenafil, or a similar drug current or previous stroke or heart problems, including chest pain, heart attack, heart failure, and aortic stenosis physical changes or anomalies affecting your penis, such as bending, scarring, and Peyronie’s disease blood cell problems, such as sickle cell anemia, multiple myeloma, and leukemia Note: For more information about the potential negative effects of Viagra, see the “Viagra side effects” section. As with all medications, the cost of Viagra can vary. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. To learn more about the cost of Viagra, refer to this article. Financial and insurance assistance: If you need financial support to pay for Viagra, or if you need help understanding your insurance coverage, help is available.

What to do in case you take too much Viagra

A savings card is available for Viagra. For more information and to find out if you’re eligible for support, visit the program website. Generic version: Viagra is available as generic sildenafil. The generic is considered to be as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.